Phase contrast and fluorescence microscopic long time recordings of living cells

Long-time recordings of living cells allow to investigate physiologic processes that occur in the range of minutes to hours. Typical examples are cell migration, differentiation and growth. In combination with multicolor fluorescent recordings, it additionally allows to investigate the changes in the distribution of cellular proteins.

Example recordings

Live cell recording of migrating and proliferating oligodendrocyte progenitor cells. Recorded at 2 frames per minute, played at 24 fps, total number of frames: 564.

Staining of MOSP, GFAP and DAPI in a neural cell culutre from rat brain

Mutli-channel fluorescent recording of a neural culture from rat brain. Green: Staining against myelin/oligodendrocyte-specific protein (MOSP, showing mature oligodendrocytes), red: glial fibrillary acidic protein (GFAP, showing astrocytes) and blue: DNA (showing all cells).

Related instruments