Projects in RUBION

Burried layers in diamond (Group Lorke, University Duisburg-Essen)

Group of Hans-Werner Becker, RUBION, Ruhr-Universität Bochum

A burried graphite layer to serve as a gate for a FET should be produced by the implantation of carbon in diamond with an energy of 100 keV to open the possibility to stabilize and manipulate single NV centres.

Catalytic release of fluorescent dyes in bacteria

Bioinorganic Chemistry, Faculty for Chemistry and Biochemistry, Ruhr University Bochum

We aim to study the catalytic release of different fluorescent dyes in B. subtitles bacteria. The bacterial cells shall be incubated with different dyes, which are non-fluorescent as they are in a protected state. Upon addition of a Ruthenium compound as catalyst the fluorescent dye will be released. Fluorescent intensity is to be determined over a time course of 24 h. In order to apply different concentrations and different dyes, the plate reader from Prof. Bandow's group will be used. Potentially, these studies will also be carried out in life cells under a fluorescent microscope.

Funded by: None / internal funds from RUB

Functionalized Nanodiamonds for Biomedical Research and Therapy

Radiobiology MHH, Molecular Oncology and Radiobiology, Ruhr-University Bochum

Several groups from various German universities are involved in this project, which is sponsored by a grant of the Volkswagen Foundation. The aim is to modify nanodiamonds in order to use them for diagnostic as well as therapeutic purposes. On the one hand, our research group is investigating the biocompatibility of these nanodiamonds as an indispensable prerequisite for their use in humans. On the other hand, we want to clarify whether nanodiamonds doped with the strong beta-emitter 32P can be used for radiotherapy as a kind of intracellular brachytherapy.

Funtionalized Nanodiamonds for Biomedical Research and Therapy

Nanoscopy, RUBION, Ruhr-Universität Bochum

Nanodiamonds are biocompatible nanoparticles, which can be functionalized by manifold surface modifications. Therefore, they are an excellent candidate for biomedical and even therapeutic applications. Here we aim at developing nanodiamonds labeled by different lattice modifications, such that they are detectable by various techniques, from microscopy and radiography to magnet resonance imaging. Modifying the nanodiamond lattice instead of its surface ensures that the nanoparticle and its label do not dissolve in physiologic environment. Additionally, it does not alter its interactions with the environment and hence the biocompatibility of the nanoparticle is preserved. A nanoparticle that is not detectable due to surface but to lattice modifications for the first time allows comparable investigations from the subcellular to organism level, eventually leading to the development of nanodiamond based tools for biomedical and therapeutic applications.

Funded by: VolkswagenStiftung

He4 implantation ino thin aluminum foils

Group of Hans-Werner Becker, RUBION, Ruhr-Universität Bochum

For experiments at the superconducting cyclotron at the Laboratory Nazionali del Sud of the INFN in Catania He4 targets are prepared by He implantation into thin aluminum foils. The goal is to have a high He concentration in foils as thin as possible. The foils will be characterized by RBS with protons.

Production of a 12C Target for Nuclear Astrophysics

Group of Hans-Werner Becker, RUBION, Ruhr-Universität Bochum

A 12C Target for Nuclear Astrophysics purposes will be produced by implantation with energies between 30 and 50 keV at the 100 keV implanter

Roughness measurements of cryopreserved neural cells

Electrobiochemistry of Neural Cells, Department of Biochemistry II, Ruhr-Universität Bochum

In order to investigate, whether cryopreservation invokes changes in the membrane of neural cells, roughness measurements using scanning ion conductance microscopy are performed.