Characterisation of Membrane ATPases

ATPases are integral membrane proteins that play a pivotal role in cell homeostasis by pumping substrates as diverse as ions and lipids. Although several members of this group are well-studied, many molecular details involved in their working mechanism and regulation on the molecular level still remain unsolved. In combination with transporter mutants we expect to gain a molecular understanding of how ATP, pH, the ion concentration, and the lipid environment regulate these transporters.

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Theses

  • Kevin Cömer Boga: Optimization of model membranes for protein-mediated sterol transport (Bachelor's thesis, 2019)